Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports

Infectious Diseases and Tropical Medicine 2015; 1 (2): e100

  Topic: Bacterial Infections     Category:

Di Carlo P.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close
, Trizzino M.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy
marcellotrizzino@hotmail.it Close
, Giarratano A.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Giammanco A.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close
, Montalto F.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Raineri M.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Dones F.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Bonura C.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close

Abstract

We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The article presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibiotics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.

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To cite this article

Di Carlo P.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close
, Trizzino M.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy
marcellotrizzino@hotmail.it Close
, Giarratano A.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Giammanco A.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close
, Montalto F.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Raineri M.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Dones F.
Intensive Care Unit, Department of Emergency, Critical Care and Neuroscience, University of Palermo, Palermo, Italy Close
, Bonura C.
Department of Sciences for Health Promotion “G. D’Alessandro”, University of Palermo, Palermo, Italy Close
Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports

Infectious Diseases and Tropical Medicine 2015; 1 (2): e100

Publication History

Published online: 15 Jul 2015