We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The article presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibiotics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.
To cite this article
Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports
Infectious Diseases & Tropical Medicine 2015; 1 (2): e100
Published online: 15 Jul 2015