The incidence of candidemia in the neonatal intensive care unit (NICU) is steadily increasing, with an estimated incidence of 1.6 to 9% in very-low-birth-weight infants and 15% in extremely-low-birth-weight infants. Here we report the case of a refractory candidemia by Candida parapsilosis successfully treated with caspofungin in a premature infant. The use of lysis centrifugation blood culture permitted to isolate Candida parapsilosis and the infant responded well to antifungal treatment, with a prompt improvement of his clinical condition. Caspofungin seems to be a valid option for infants with invasive candidiasis refractory to conventional antifungal therapy.
To cite this article
Candida parapsilosis responsive to caspofungin in a preterm infant
Infectious Diseases & Tropical Medicine 2015; 1 (3): e138
Published online: 01 Oct 2015